HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00234(AIDA Antibody) at dilution of 1:600
IP Result of anti-AIDA (IP:FNab00234, 3ug; Detection:FNab00234 1:600) with HeLa cells lysate 4000ug.
Background
Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling(By similarity).