Products
VDR antibody
- SPECIFICATIONS
- CITATIONS
- Product Name
- VDR antibody
- Catalogue No.
- FNab09390
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- vitamin D (1, 25- dihydroxyvitamin D3) receptor
- Alternative Names
- NR1I1 antibody, VDR antibody, Vitamin D3 receptor antibody
- UniProt ID
- P11473
- Observed MW
- 43 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Validated Images
PC-3 cells were subjected to SDS PAGE followed by western blot with FNab09390( VDR Antibody) at dilution of 1:1000
- Background
- This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins.
IF: 7.54
- Journal:
- Cell Communication and Signaling
- Author:
- Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, Guizhou, 563000, China
- Cited Date:
- 2023-06-02
- Product: