HL-60 cells were subjected to SDS PAGE followed by western blot with FNab08603(TET2 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human placenta using FNab08603(TET2 antibody) at dilution of 1:200
Background
The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene.