Rat liver tissue were subjected to SDS PAGE followed by western blot with FNab08264(ST3GAL3 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver injury using FNab08264(ST3GAL3 antibody) at dilution of 1:100
Background
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Mutations in this gene have been associated with autosomal recessive nonsymdromic mental retardation-12 (MRT12). Multiple transcript variants encoding several different isoforms have been found for this gene.