mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab06716(PPP2R2A antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat kidney using FNab06716(PPP2R2A antibody) at dilution of 1:100
Background
The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants have been described.