HeLa cells were subjected to SDS PAGE followed by western blot with FNab04667(KYNU antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse heart using FNab04667(KYNU antibody) at dilution of 1:100
Background
Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants.