A549 cells were subjected to SDS PAGE followed by western blot with FNab04335(INSL3 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human prostate using FNab04335(INSL3 antibody) at dilution of 1:50
Background
This gene encodes a member of the insulin-like hormone superfamily. The encoded protein is mainly produced in gonadal tissues. Studies of the mouse counterpart suggest that this gene may be involved in the development of urogenital tract and female fertility. This protein may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. Mutations in this gene may lead to cryptorchidism. Alternate splicing results in multiple transcript variants.