Products
CD45 antibody
Synonyms: | B220 antibody, CD45 antibody, CD45R antibody, GP180 antibody, L CA antibody, LCA antibody, Leukocyte common antigen antibody, LY5 antibody, PTPRC antibody, RPTPC antibody, T200 antibody | ||
Catalogue No.: | FNab01484 | Reactivity: | Human, Mouse, Rat |
Host: | Rabbit | Tested Application: | ELISA, IHC, WB |
Clonality: | polyclonal | Isotype: | IgG |
- SPECIFICATIONS
- CITATIONS
- Product Name
- CD45 antibody
- Catalogue No.
- FNab01484
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- protein tyrosine phosphatase, receptor type, C
- Alternative Names
- B220 antibody, CD45 antibody, CD45R antibody, GP180 antibody, L CA antibody, LCA antibody, Leukocyte common antigen antibody, LY5 antibody, PTPRC antibody, RPTPC antibody, T200 antibody
- UniProt ID
- P08575
- Observed MW
- 190 kDa
Application
- Tested Applications
- ELISA, IHC, WB
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab01484( CD45 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lymphoma using FNab01484(CD45 antibody) at dilution of 1:50
- Background
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.
IF: 3
- Journal:
- Archives of Oral Biology
- Author:
- Department of Dentistry, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia
- Cited Date:
- 2023-09-28
- Product: