ACVR1C antibody

Category: Research Area:
Synonyms：Activin receptor type-1C|Activin receptor type IC (ACTR-IC)|Activin receptor-like kinase 7 (ALK-7)|ACVR1C|ALK7 antibody
Catalogue No.：FNab00130Reactivity：Human, Mouse, Rat
Host：RabbitTested Application：ELISA, WB, IHC
Clonality：polyclonalIsotype：IgG
Manual MSDS
  • SPECIFICATIONS
Product Name
ACVR1C antibody
Catalogue No.
FNab00130
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
activin A receptor, type IC
Alternative Names
Activin receptor type-1C|Activin receptor type IC (ACTR-IC)|Activin receptor-like kinase 7 (ALK-7)|ACVR1C|ALK7 antibody
UniProt ID
Q8NER5
Observed MW
60 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:100 - 1:200
Validated Images
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab00130(ACVR1C antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach using FNab00130(ACVR1C antibody) at dilution of 1:100
Background
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).
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