293T cells were subjected to SDS PAGE followed by western blot with FNab05074(MDH2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human live tissue slide using FNab05074(MDH2 antibody) at dilution of 1:100
Background
Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene.