Products

RAD51 antibody

Synonyms:RAD51A antibody, RECA antibody
Catalogue No.:FNab10134Reativity:Human
Host:RabbitTested Application:ELISA, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
RAD51 antibody
Catalogue No.
FNab10134
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
RAD51 homolog
Alternative Names
RAD51A antibody, RECA antibody
UniProt ID
Q06609
Observed MW
37 kDa
Application
Tested Applications
ELISA, IHC
Recommended dilution
IHC: 1:50-1:500
Validated Images
Immunohistochemistry of paraffin-embedded human ovary cancer tissue slide using FNab10134(RAD51 Antibody) at dilution of 1:200
Background
Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange(PubMed:26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.