Products

anti- RAD51 antibody

FNab10134 Catalogue No.
Synonyms
RAD51A, RECA
Host
Rabbit
Reactivity
Human
Isotype
IgG
Tested Application
ELISA, IHC
Product Information
Product Name
anti- RAD51 antibody
Catalogue No.
FNab10134
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange(PubMed:26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.
Immunogen Information
Immunogen
RAD51 homolog
Synonyms
RAD51A, RECA
Observed MW
37 kDa
Application
Tested Application
ELISA, IHC
Recommended dilution
IHC: 1:50-1:500
Uniprot information
UniProt ID
Q06609
Images
Immunohistochemistry of paraffin-embedded human ovary cancer tissue slide using FNab10134(RAD51 Antibody) at dilution of 1:200