Products
UVRAG antibody
- Product Name
- UVRAG antibody
- Catalogue No.
- FNab09352
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- UV radiation resistance associated gene
- Alternative Names
- UV radiation resistance-associated gene protein|p63|UVRAG antibody
- UniProt ID
- Q9P2Y5
- Observed MW
- 100 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09352(UVRAG antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver injury using FNab09352(UVRAG antibody) at dilution of 1:100
- Background
- This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.
