HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab07537(RUVBL1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse liver tissue slide using FNab07537( RUVBL1 Antibody) at dilution of 1:200
Immunofluorescence analysis of A549 cells using FNab07537( RUVBL1 Antibody). Blue: DAPI for nuclear staining.
Background
This gene encodes a protein that has both DNA-dependent ATPase and DNA helicase activities and belongs to the ATPases associated with diverse cellular activities (AAA+) protein family. The encoded protein associates with several multisubunit transcriptional complexes and with protein complexes involved in both ATP-dependent remodeling and histone modification. Alternate splicing results in multiple transcript variants.