PEG10 antibody

Synonyms:EDR antibody, KIAA1051 antibody, MAR2 antibody, MART2 antibody, MEF3L1 antibody, RGAG3 antibody
Catalogue No.:FNab06302Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PEG10 antibody
Catalogue No.
FNab06302
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
paternally expressed 10
Alternative Names
EDR antibody, KIAA1051 antibody, MAR2 antibody, MART2 antibody, MEF3L1 antibody, RGAG3 antibody
UniProt ID
Q86TG7
Observed MW
50 kDa,100 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab06302(PEG10 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human breast cancer using FNab06302(PEG10 antibody) at dilution of 1:100
Background
Prevents apoptosis in hepatocellular carcinoma(HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation(By similarity). May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein(MBP) promoter(By similarity).