Products
FANCL antibody
- Product Name
- FANCL antibody
- Catalogue No.
- FNab03010
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Fanconi anemia, complementation group L
- Alternative Names
- E3 ubiquitin-protein ligase FANCL|Fanconi anemia group L protein|Fanconi anemia-associated polypeptide of 43 kDa (FAAP43)|RING-type E3 ubiquitin transferase FANCL|FANCL|PHF9 antibody
- UniProt ID
- Q9NW38
- Observed MW
- 38 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:200 - 1:2000; IHC: 1:20 - 1:200
Validated Images
human brain tissue were subjected to SDS PAGE followed by western blot with FNab03010(FANCL antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse stomach using FNab03010( FANCL Antibody) at dilution of 1:50
- Background
- The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms.
