Products
CD3E antibody
- Product Name
- CD3E antibody
- Catalogue No.
- FNab01459
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 2E4
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- CD3e molecule, epsilon (CD3-TCR complex)
- Alternative Names
- T-cell surface glycoprotein CD3 epsilon chain|T-cell surface antigen T3/Leu-4 epsilon chain|CD3E|T3E antibody
- UniProt ID
- P07766
- Observed MW
- 23 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF, FC
- Recommended dilution
- WB: 1:2000 - 1:20000; IHC: 1:1000 - 1:10000; IF: 1:50 - 500
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01459( CD3E Antibody) at dilution of 1:10000
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab01459( CD3E Antibody) at dilution of 1:8000
- Background
- CD3 is a complex of proteins that directly associates with the T cell receptor (TCR). The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction. CD3 is considered to be a pan-T cell marker for detection of normal and neoplastic T cells. This anti-CD3 is a monoclonal antibody directed against the epsilon chain of human CD3 molecule.
