TRPV1 antibody

Synonyms:TRPV1 antibody, VR1 antibody
Catalogue No.:FNab10732Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
TRPV1 antibody
Catalogue No.
FNab10732
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
centromere protein H
Alternative Names
TRPV1 antibody, VR1 antibody
UniProt ID
Q8NER1
Observed MW
110 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:200-1:2000; IHC: 1:20-1:200
Validated Images
293T cell lysates were subjected to SDS PAGE followed by western blot with FNab10732(TRPV1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon tissue slide using FNab10732(TRPV1 antibody) at dilution of 1:100
Background
Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene.