Products
PFKFB3 antibody
- Product Name
- PFKFB3 antibody
- Catalogue No.
- FNab10422
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
- Alternative Names
- 6PF 2 K/Fru 2 antibody, 6 P2ase 3 antibody, FLJ37326 antibody, IPFK2 antibody, PFK/FBPase 3 antibody, PFK2 antibody, PFKFB3 antibody
- UniProt ID
- Q16875
- Observed MW
- 58 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:200-1:1000; IHC: 1:50 - 1:200
Validated Images
A431 cells were subjected to SDS PAGE followed by western blot with FNab10422(PFKFB3 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded rat lung using FNab10422(PFKFB3 antibody) at dilution of 1:100
- Background
- PFKFB3, also named as NY-REN-56 and iPFK-2, plays a role in glucose metabolism. It synthesis and degradation of fructose 2,6-bisphosphate. Endogenously generated adenosine cooperates with bacterial components to increase PFKFB3 isozyme activity, resulting in greater fructose 2,6-bisphosphate accumulation. PFKFB3 is required for increased growth, metabolic activity and is regulated through active JAK2 and STAT5. This antibody is specific to PFKFB3.
