Various lysates were subjected to SDS PAGE followed by western blot with FNab10363(SUB1 antibody) at dilution of 1:1000
Background
General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA(ds DNA).