Huntingtin antibody

Synonyms:HD antibody, HD protein antibody, HTT antibody, Huntingtin antibody, Huntington disease protein antibody, IT15 antibody
Catalogue No.:FNab09844Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IF, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
Huntingtin antibody
Catalogue No.
FNab09844
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
Huntingtin
Alternative Names
HD antibody, HD protein antibody, HTT antibody, Huntingtin antibody, Huntington disease protein antibody, IT15 antibody
UniProt ID
P42858
Observed MW
348 kDa
Application
Tested Applications
ELISA, WB, IF, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50-1:500; IF: 1:50-1:500
Validated Images
Various cells were subjected to SDS PAGE followed by western blot with FNab09844( Huntingtin Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain tissue slide using FNab09844( Huntingtin antibody) at dilution of 1:200
Immunofluorescent analysis of (4% PFA) fixed human brain tissue using FNab09844 (Huntingtin antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
Background
HTT(huntingtin), also named as HD and IT15, belongs to the huntingtin family. HTT may play a role in microtubule-mediated transport or vesicle function. Defects in HTT are the cause of Huntington disease (HD) which is an autosomal dominant neurodegenerative disorder characterized by involuntary movements (chorea), general motor impairment, psychiatric disorders and dementia.