Various cells were subjected to SDS PAGE followed by western blot with FNab09844( Huntingtin Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain tissue slide using FNab09844( Huntingtin antibody) at dilution of 1:200
Immunofluorescent analysis of (4% PFA) fixed human brain tissue using FNab09844 (Huntingtin antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
Background
HTT(huntingtin), also named as HD and IT15, belongs to the huntingtin family. HTT may play a role in microtubule-mediated transport or vesicle function. Defects in HTT are the cause of Huntington disease (HD) which is an autosomal dominant neurodegenerative disorder characterized by involuntary movements (chorea), general motor impairment, psychiatric disorders and dementia.