Products
ZIP kinase antibody
- Product Name
- ZIP kinase antibody
- Catalogue No.
- FNab09640
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- death-associated protein kinase 3
- Alternative Names
- DAP kinase 3 antibody, DAP like kinase antibody, DAPK3 antibody, Dlk antibody, ZIP kinase antibody, ZIPK antibody
- UniProt ID
- O43293
- Observed MW
- 53kd
Application
- Tested Applications
- ELISA, WB, IF
- Recommended dilution
- WB: 1:200-1:1000; IF: 1:20-1:200
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab09640( ZIP kinase antibody） at dilution of 1:300
- Background
- ZIP kinase, also named as ZIPK and Dlk, belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and DAP kinase subfamily. ZIP kinase is a Serine/threonine kinase which acts as a positive regulator of apoptosis. ZIP kinasephosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. ZIP kinase regulates myosin light chain phosphatase through phosphorylation of MYPT1 thereby regulating the assembly of the actin cytoskeleton, cell migration, invasiveness of tumor cells, smooth muscle contraction and neurite outgrowth. It catalyze the reaction: ATP + a protein = ADP + a phosphoprotein.
