Zinc-alpha-2-glycoprotein antibody

Synonyms:AZGP1 antibody, ZA2G antibody, ZAG antibody, Zinc-alpha-2-glycoprotein antibody, Zn alpha 2 glycoprotein antibody, Zn alpha 2 GP antibody, ZNGP1 antibody
Catalogue No.:FNab09639Reactivity:Human
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
Zinc-alpha-2-glycoprotein antibody
Catalogue No.
FNab09639
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
alpha-2-glycoprotein 1, zinc-binding
Alternative Names
AZGP1 antibody, ZA2G antibody, ZAG antibody, Zinc-alpha-2-glycoprotein antibody, Zn alpha 2 glycoprotein antibody, Zn alpha 2 GP antibody, ZNGP1 antibody
UniProt ID
P25311
Observed MW
41 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:5000; IF: 1:20-1:200; IHC: 1:20-1:200
Validated Images
PC-3 cells were subjected to SDS PAGE followed by western blot with FNab09639(AZGP1 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human breast cancer using FNab09639(AZGP1 antibody) at dilution of 1:100
Background
Zinc-alpha-2-glycoprotein(AZGP1) is a 41-kDa soluble protein normally found in body fluids, functions as a lipid mobilizing factor(PMID: 19188554). It is known to be expressed in the secretory epithelia of the liver, lung, breast, GI tract and sweat glands, sharing significant structural similarity with the class I major histocompatibility complex(MHC) antigens(PMID: 3422450). AZGP1 is involved in carcinogenesis and differentiation. Altered expression of AZGP1 has been reported in breast cancer, prostate cancer and lung adenocarcinoma, hepatocellular carcinoma, pancreatic carcinoma and oral tumors(PMID: 22625427).