Products
YWHAB antibody
- Product Name
- YWHAB antibody
- Catalogue No.
- FNab09575
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
- Alternative Names
- 14 3 3 antibody, 14 3 3 alpha antibody, 14 3 3 protein beta/alpha antibody, YWHAB antibody
- UniProt ID
- P31946
- Observed MW
- 28 kDa
Application
- Tested Applications
- ELISA, IHC
- Recommended dilution
- IHC: 1:20-1:200
Validated Images
Immunohistochemical of paraffin-embedded human colon cancer using FNab09575(YWHAB antibody) at dilution of 1:50
- Background
- Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form(by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activatation of MAP kinases via AKAP13.
