Products
XRN2 antibody
- Product Name
- XRN2 antibody
- Catalogue No.
- FNab09557
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- 5'-3' exoribonuclease 2
- Alternative Names
- XRN2 antibody, DHM1 like protein antibody, DHP protein antibody, 5' 3' exoribonuclease 2 antibody, 5 3 exoribonuclease 2 antibody
- UniProt ID
- Q9H0D6
- Observed MW
- 108 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:200-1:1000
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab09557(XRN2 antibody) at dilution of 1:200
- Background
- Possesses 5'->3' exoribonuclease activity(By similarity). May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II(RNAp II) transcription termination R-loops formed by G-rich pause sites(PubMed:21700224).
