Products
USP44 antibody
- Product Name
- USP44 antibody
- Catalogue No.
- FNab09334
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ubiquitin specific peptidase 44
- Alternative Names
- Deubiquitinating enzyme 44 antibody, DKFZp434D0127 antibody, FLJ14528 antibody, Ubiquitin thiolesterase 44 antibody, USP44 antibody
- UniProt ID
- Q9H0E7
- Observed MW
- 81 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:5000
Validated Images
human placenta tissue were subjected to SDS PAGE followed by western blot with FNab09334(USP44 antibody) at dilution of 1:500
- Background
- Deubiquitinase that plays a key regulatory role in the spindle assembly checkpoint or mitotic checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome(APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex(also named mitotic checkpoint complex), thereby preventing premature activation of the APC/C. Promotes association of MAD2L1 with CDC20 and reinforces the spindle assembly checkpoint. Acts as a negative regulator of histone H2B(H2BK120ub1) ubiquitination.
