Products
USP14 antibody
- Product Name
- USP14 antibody
- Catalogue No.
- FNab09310
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ubiquitin specific peptidase 14(tRNA-guanine transglycosylase)
- Alternative Names
- Deubiquitinating enzyme 14 antibody, TGT antibody, Ubiquitin thiolesterase 14 antibody, USP14 antibody
- UniProt ID
- P54578
- Observed MW
- 52-60 kDa
Application
- Tested Applications
- ELISA, WB, IF, FC
- Recommended dilution
- WB: 1:500-1:5000; IP: 1:500-1:5000; IF: 1:10-1:100
Validated Images
mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab09310(USP14 antibody) at dilution of 1:300
- Background
- Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation(ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions(NMJs).
