Products
USP1 antibody
- Product Name
- USP1 antibody
- Catalogue No.
- FNab09302
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ubiquitin specific peptidase 1
- Alternative Names
- Deubiquitinating enzyme 1 antibody, hUBP antibody, ubiquitin specific peptidase 1 antibody, Ubiquitin thiolesterase 1 antibody, UBP antibody, USP1 antibody
- UniProt ID
- O94782
- Observed MW
- 100 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:200-1:2000; IHC: 1:20-1:200；IP: 1:200-1:1000
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab09302(USP1 antibody) at dilution of 1:300
IP Result of anti-USP1 (IP:FNab09302, 3ug; Detection:FNab09302 1:300) with HEK-293 cells lysate 3200ug.
Immunohistochemistry of paraffin-embedded human cervical cancer using FNab09302(USP1 antibody) at dilution of 1:100
- Background
- Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2(PubMed:15694335). Also involved in PCNA-mediated translesion synthesis(TLS) by deubiquitinating monoubiquitinated PCNA(PubMed:16531995). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity(PubMed:18082604, PubMed:26388029).
