Products
UNC13A/Munc13-1 antibody
- Product Name
- UNC13A/Munc13-1 antibody
- Catalogue No.
- FNab09255
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- unc-13 homolog A(C. elegans)
- Alternative Names
- KIAA1032 antibody, Munc13 1 antibody, Protein unc 13 homolog A antibody, unc 13 homolog A(C. elegans) antibody, UNC13A antibody
- UniProt ID
- Q9UPW8?
- Observed MW
- 193 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:5000
Validated Images
human brain tissue were subjected to SDS PAGE followed by western blot with FNab09255(UNC13A antibody) at dilution of 1:300
- Background
- UNC13A, also named as KIAA1032, belongs to the unc-13 family. It plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. UNC13A is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool(RRP). It is essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. UNC13A is also involved in secretory granule priming in insulin secretion. The antibody is specific to UNC13A.
