Products
TXNRD1 antibody
- Product Name
- TXNRD1 antibody
- Catalogue No.
- FNab09133
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- thioredoxin reductase 1
- Alternative Names
- GRIM 12 antibody, GRIM12 antibody, KDRF antibody, thioredoxin reductase 1 antibody, Thioredoxin reductase TR1 antibody, TR antibody, TR1 antibody, TRXR1 antibody, TXNR antibody, TXNRD1 antibody
- UniProt ID
- Q16881
- Observed MW
- 54 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF, FC, IP
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100; IP: 1:200-1:2000
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09133(TXNRD1 antibody) at dilution of 1:500
IP Result of anti-TXNRD1 (IP:FNab09133, 3ug; Detection:FNab09133 1:500) with Jurkat cells lysate 1500ug.
Immunohistochemistry of paraffin-embedded human breast cancer using FNab09133(TXNRD1 antibody) at dilution of 1:100
- Background
- Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
