Products

TRPV6 antibody

Synonyms:ABP/ZF antibody, Calcium transport protein 1 antibody, CaT L antibody, CaT like antibody, CAT1 antibody, CATL antibody, ECAC2 antibody, Epithelial calcium channel 2 antibody, HSA277909 antibody, LP6728 antibody, TRPV6 antibody, ZFAB antibody
Catalogue No.:FNab09030Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IF, WB, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
TRPV6 antibody
Catalogue No.
FNab09030
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
transient receptor potential cation channel, subfamily V, member 6
Alternative Names
ABP/ZF antibody, Calcium transport protein 1 antibody, CaT L antibody, CaT like antibody, CAT1 antibody, CATL antibody, ECAC2 antibody, Epithelial calcium channel 2 antibody, HSA277909 antibody, LP6728 antibody, TRPV6 antibody, ZFAB antibody
UniProt ID
Q9H1D0
Observed MW
82 kDa,70 kDa
Application
Tested Applications
ELISA, IF, WB, IP
Recommended dilution
WB: 1:500-1:5000; IP: 1:200-1:1000; IF: 1:10-1:100
Validated Images
human placenta tissue were subjected to SDS PAGE followed by western blot with FNab09030(TRPV6 Antibody) at dilution of 1:1000
IP Result of anti-TRPV6 (IP:FNab09030, 4ug; Detection:FNab09030 1:300) with mouse kidney tissue lysate 4000ug.
Background
Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine(PubMed:11097838, PubMed:11278579, PubMed:11248124 PubMed:15184369, PubMed:23612980). Important for normal Ca(2+) ion homeostasis in the body, including bone and skin(By similarity). The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification(PubMed:15184369). Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism; the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.