Products
Transferrin antibody
- Product Name
- Transferrin antibody
- Catalogue No.
- FNab08929
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- transferrin
- Alternative Names
- Beta 1 metal binding globulin antibody, DKFZp781D0156 antibody, PRO1557 antibody, PRO2086 antibody, Serotransferrin antibody, Siderophilin antibody, TF antibody, Transferrin antibody
- UniProt ID
- P02787
- Observed MW
- 77 kDa
Application
- Tested Applications
- ELISA, WB, IHC,IF
- Recommended dilution
- WB: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab08929(TF antibody) at dilution of 1:400
Immunohistochemistry of paraffin-embedded human hepatocirrhosis using FNab08929(TF antibody) at dilution of 1:50
- Background
- Serotransferrin(TF) is a 77 kDa secreted protein which is also named as transferrin, siderophilin, beta-1 metal-binding globulin and belongs to a family of homologous iron-binding glycoproteins that encompasses lactoferrin(found both intracellular and in secretions, including milk), melanotrasferrin(present on melanoma cells) and ovotransferrin(present in egg white). TF is a multi-function protein with a primary role in transporting iron in a safe, redox-inactive state from absorption to utilization or storage sites around the body. The association of Tf with the immune system derives from its ability to restrict serum free-iron levels, creating low-iron environments where the infection capacity of pathogenic microorganisms is limited. TF is expressed predominantly in the liver and secreted in plasma, but lower amounts can be synthesized in other tissues such as the brain and the testis
