mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with FNab08820(TNFAIP8L2 antibody) at dilution of 1:500
IP Result of anti-TIPE2 (IP:FNab08820, 3ug; Detection:FNab08820 1:500) with mouse cerebellum tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human lymphoma using FNab08820(TNFAIP8L2 antibody) at dilution of 1:50
Background
Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis(By similarity).