Products
TCTN1 antibody
- Product Name
- TCTN1 antibody
- Catalogue No.
- FNab08567
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- tectonic family member 1
- Alternative Names
- TECT1 antibody
- UniProt ID
- Q2MV58
- Observed MW
- 55-64 kDa
Application
- Tested Applications
- ELISA, WB, IF, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
mouse embryo tissue were subjected to SDS PAGE followed by western blot with FNab08567(TCTN1 antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab08567(TCTN1 Antibody) at dilution of 1:50
- Background
- Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Regulator of Hedgehog(Hh), required for both activation and inhibition of the Hh pathway in the patterning of the neural tube. During neural tube development, it is required for formation of the most ventral cell types and for full Hh pathway activation. Functions in Hh signal transduction to fully activate the pathway in the presence of high Hh levels and to repress the pathway in the absence of Hh signals. Modulates Hh signal transduction downstream of SMO and RAB23(By similarity).
