Products

SUN1 antibody

Synonyms:KIAA0810 antibody, UNC84A antibody
Catalogue No.:FNab08392Reativity:Human
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
SUN1 antibody
Catalogue No.
FNab08392
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.1% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
unc-84 homolog A(C. elegans)
Alternative Names
KIAA0810 antibody, UNC84A antibody
UniProt ID
O94901
Observed MW
90 kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:5000
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab08392(UNC84A Antibody) at dilution of 1:1000
Background
Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration(INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes(NPCs)(By similarity). Required for efficient localization of SYNE4 in the nuclear envelope(By similarity).