3T3-L1 cells were subjected to SDS PAGE followed by western blot with FNab08319(STEAP4 antibody) at dilution of 1:1000
IP result of anti-STEAP4(IP:FNab08319, 4ug; Detection:FNab08319 1:1000) with 3T3-L1 cells lysate 1200 ug
Immunohistochemistry of paraffin-embedded human prostate cancer using FNab08319(STEAP4 antibody) at dilution of 1:50
Background
Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses(By similarity). Associated with obesity and insulin-resistance. Involved in inflammatory arthritis, through the regulation of inflammatory cytokines. Inhibits anchorage-independent cell proliferation.