Products
SMN antibody
- Product Name
- SMN antibody
- Catalogue No.
- FNab08033
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 3D2
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- survival of motor neuron 2, centromeric
- Alternative Names
- C BCD541 antibody, Component of gems 1 antibody, FLJ76644 antibody, Gemin 1 antibody, SMN antibody, SMN1 antibody, SMN1 antibody, SMN antibody, SMN2 antibody, SMNC antibody, SMNT antibody, Survival motor neuron protein antibody
- UniProt ID
- Q16637
- Observed MW
- 38kd
Application
- Tested Applications
- ELISA, WB, IF
- Recommended dilution
- WB: 1:1000-1:6000; IF: 1:50-1:500
Validated Images
A375 cells were subjected to SDS PAGE followed by western blot with FNab08033(SMN antibody) at dilution of 1:3000
Immunofluorescent analysis of ( -20℃ Ethanol) fixed HEK-293 cells using FNab08033 (SMN antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated Goat Anti-Mouse IgG(H+L)
- Background
- The survival of motor neurons(SMN) genes are the disease genes of spinal muscular atrophy(SMA), a common motor neuron degenerative disease. The level of SMN protein correlates with phenotypic severity of SMA. SMA patients lack a functional SMN1 gene, but they possess an intact SMN2 gene, which though nearly identical to SMN1, is only partially functional, because a large majority of SMN2 transcripts lack exon 7, resulting in production of a truncated, less stable SMN protein. This antibody can recognize human,mouse and rat SMN.
