Products
SMG5 antibody
- Product Name
- SMG5 antibody
- Catalogue No.
- FNab08025
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Smg-5 homolog, nonsense mediated mRNA decay factor
- Alternative Names
- EST1 like protein B antibody, EST1B antibody, hSMG 5 antibody, KIAA1089 antibody, LPTS interacting protein antibody, LPTS RP1 antibody, LPTSRP1 antibody, Protein SMG5 antibody, RP11 54H19.7 antibody, SMG 5 antibody, SMG 5 homolog antibody, SMG5 antibody
- UniProt ID
- Q9UPR3
- Observed MW
- 114 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:2000
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab08025(SMG5 antibody) at dilution of 1:600
- Background
- Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A(PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity.
