Products
SETDB2 antibody
- Product Name
- SETDB2 antibody
- Catalogue No.
- FNab07772
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- SET domain, bifurcated 2
- Alternative Names
- C13orf4 antibody, CLLD8 antibody, KMT1F antibody
- UniProt ID
- Q96T68
- Observed MW
- 101 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:2000
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab07772( SETDB2 Antibody) at dilution of 1:300
- Background
- Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3(H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1(CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.
