mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab07660(SCUBE3 antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human kidney using FNab07660(SCUBE3 antibody) at dilution of 1:50
Background
Binds to TGFBR2 and activates TGFB signaling. In lung cancer cells, could serve as an endogenous autocrine and paracrine ligand of TGFBR2, which could regulate TGFBR2 signaling and hence modulate epithelial-mesenchymal transition and cancer progression.