Products
RCC1 antibody
- Product Name
- RCC1 antibody
- Catalogue No.
- FNab07209
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- regulator of chromosome condensation 1
- Alternative Names
- CHC1 antibody
- UniProt ID
- P18754
- Observed MW
- 50 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP, IF
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab07209(SNHG3-RCC1 antibody) at dilution of 1:300
IP Result of anti-RCC1 (IP:FNab07209, 3ug; Detection:FNab07209 1:1500) with HeLa cells lysate 3000ug.
Immunohistochemistry of paraffin-embedded human ovary tumor using FNab07209(SNHG3-RCC1 antibody) at dilution of 1:100
- Background
- Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex(together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
