Products
RCC1 antibody
- Product Name
- RCC1 antibody
- Catalogue No.
- FNab07208
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- regulator of chromosome condensation 1
- Alternative Names
- Regulator of chromosome condensation|Cell cycle regulatory protein|Chromosome condensation protein 1|RCC1|CHC1 antibody
- UniProt ID
- P18754
- Observed MW
- 50 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP, IF
- Recommended dilution
- WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab07208(SNHG3-RCC1 antibody) at dilution of 1:300
IP Result of anti-RCC1 (IP:FNab07208, 3ug; Detection:FNab07208 1:1000) with HEK-293 cells lysate 1000ug.
Immunohistochemistry of paraffin-embedded human ovary tumor using FNab07208(SNHG3-RCC1 antibody) at dilution of 1:100
- Background
- CHC1, also named as RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human RCC1.
