PTPRR antibody

Synonyms:ECPTP antibody, PTPRQ antibody
Catalogue No.:FNab06947Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PTPRR antibody
Catalogue No.
FNab06947
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
protein tyrosine phosphatase, receptor type, R
Alternative Names
ECPTP antibody, PTPRQ antibody
UniProt ID
Q15256
Observed MW
32 kDa,47 kDa,65 kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:2000
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab06947(PTPRR antibody) at dilution of 1:500
Background
Sequesters mitogen-activated protein kinases(MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus(By similarity).