PSMD11 antibody

Catalogue No.:FNab06883Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IP, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PSMD11 antibody
Catalogue No.
FNab06883
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
proteasome(prosome, macropain) 26S subunit, non-ATPase, 11
UniProt ID
O00231
Observed MW
47 kDa
Application
Tested Applications
ELISA, WB, IP, IF
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab06883( PSMD11 Antibody) at dilution of 1:1000
IP Result of anti-PSMD11 (IP:FNab06883, 3ug; Detection:FNab06883 1:500) with MCF-7 cells lysate 2000ug.
Background
Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells(ESCs): its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity.