Products
POLK antibody
- Product Name
- POLK antibody
- Catalogue No.
- FNab06613
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- polymerase(DNA directed) kappa
- Alternative Names
- DINB protein antibody, DINB1 antibody, DINP antibody, DNA polymerase kappa antibody, POLK antibody, POLQ antibody
- UniProt ID
- Q9UBT6
- Observed MW
- 70 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab06613(POLK antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human cervical cancer using FNab06613(POLK antibody) at dilution of 1:100
- Background
- DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3'-5' proofreading exonuclease activity. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity.
