Products
Podocalyxin antibody
- Product Name
- Podocalyxin antibody
- Catalogue No.
- FNab06597
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- podocalyxin
- Alternative Names
- GCTM-2 antigen antibody, Gp200 antibody, Podocalyxin-like protein 1 antibody, PC antibody, PCLP-1 antibody, PODXL antibody, PCLP antibody, PCLP1 antibody
- UniProt ID
- O00592
- Observed MW
- 59 kDa
Application
- Tested Applications
- ELISA, WB, IHC, FC
- Recommended dilution
- WB: 1:500-1:1000; IHC: 1:20-1:200
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab06597(PODXL antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human kidney using FNab06597(PODXL antibody) at dilution of 1:50
- Background
- Podocalyxin, also known as podocalyxin-like protein 1(PODXL or PCLP1), is a transmembrane glycoprotein belonging to the CD34 family of sialomucins. Podocalyxin was originally identified as the major sialoprotein on podocytes of the kidney glomerulus, but was later found to be expressed on vascular endothelial cells and early hematopoietic progenitors. It Involved in the regulation of both adhesion and cell morphology. In addition, podocalyxin is highly expressed in embryonic stem cells and aberrant expression of podocalyxin has been implicated in a wide range of cancers.
