PHC2 antibody

Synonyms:EDR2 antibody, HPH2 antibody, PH2 antibody, PHC2 antibody, Polyhomeotic like protein 2 antibody
Catalogue No.:FNab06373Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB,IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PHC2 antibody
Catalogue No.
FNab06373
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
polyhomeotic homolog 2(Drosophila)
Alternative Names
EDR2 antibody, HPH2 antibody, PH2 antibody, PHC2 antibody, Polyhomeotic like protein 2 antibody
UniProt ID
Q8IXK0
Observed MW
40kd
Application
Tested Applications
ELISA, WB,IF
Recommended dilution
WB: 1:200-1:2000; IF: 1:50-1:500
Validated Images
A375 cells were subjected to SDS PAGE followed by western blot with FNab06373(PHC2 Antibody) at dilution of 1:600
Background
Component of a Polycomb group(PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.