mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab06343(PFN2 Antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab06343(PFN2 Antibody) at dilution of 1:400
Background
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.