Products
p63 antibody
- Product Name
- p63 antibody
- Catalogue No.
- FNab06088
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- tumor protein p63
- Alternative Names
- AIS antibody, B(p51A) antibody, B(p51B) antibody, CUSP antibody, EEC3 antibody, KET antibody, LMS antibody, NBP antibody, OFC8 antibody, p40 antibody, p51 antibody, p53CP antibody, p63 antibody, p73H antibody, p73L antibody, RHS antibody, SHFM4 antibody, TP53CP antibody, TP53L antibody, TP63 antibody, TP73L antibody, Tumor protein 63 antibody, tumor protein p63 antibody, Tumor protein p73 like antibody
- UniProt ID
- Q9H3D4
- Observed MW
- 45-75 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:200
Validated Images
A431 cells were subjected to SDS PAGE followed by western blot with FNab06088(TP63 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab06088(TP63 Antibody) at dilution of 1:100
- Background
- TP63, also named KET, P63, P73H, P73L and TP73L, belongs to the p53 family. It is a homologue of the tumor suppressor p53 and p73 genes. It is involved in malignancy acquisition and maintenance of cells. Unlike p53, the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis. TP63 acts as a sequence specific DNA binding transcriptional activator or repressor. TP63 has 12 isoforms with MW 40kd(P40), 50kd(P60),63kd(P63) and 73kd(P73L). It is Nuclear stain.
