Products
NUAK2 antibody
- Product Name
- NUAK2 antibody
- Catalogue No.
- FNab05886
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- NUAK family, SNF1-like kinase, 2
- Alternative Names
- OMPHK2 antibody, SNARK antibody
- UniProt ID
- Q9H093
- Observed MW
- 70 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
Y79 cells were subjected to SDS PAGE followed by western blot with FNab05886(NUAK2 antibody) at dilution of 1:400
Immunohistochemistry of paraffin-embedded human kidney using FNab05886(NUAK2 antibody) at dilution of 1:50
- Background
- Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1.
