Products

NKIRAS2 antibody

Synonyms:KBRAS2 antibody
Catalogue No.:FNab05746Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
NKIRAS2 antibody
Catalogue No.
FNab05746
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
NFKB inhibitor interacting Ras-like 2
Alternative Names
KBRAS2 antibody
UniProt ID
Q9NYR9
Observed MW
22 kDa
Application
Tested Applications
ELISA, WB, IF
Recommended dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab05746( NKIRAS2 Antibody) at dilution of 1:600
Background
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta(NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP-and GDP-bound forms block phosphorylation of NFKBIB(By similarity).